Hard Cell

Ah, who can forget the first time we directed the guy on the screen to walk across a narrow catwalk suspended over lava, only to have the guy turn to the screen and say, "Eat my fuckmeat, muchacho! In case you didn't know, lava is hot." 

Hard Cell is a third-person game where you control an avatar that isn't particularly happy about being controlled. You can see the character and you can give him commands, but he doesn't necessarily agree with your goal. 

Doing a good job of not getting your character hurt or killed will make him happier, filling your “Rapport Meter." Filling the meter makes him faster, more responsive, and overall more willing to work with you rather than against you. But lead him into dead ends, forget to take time to find food, fail to look out for his safety ...

... and things get ugly. 

You're working with a deep (that is, well-written) and complex character, operating from the most advanced A.I. ever to appear in a game. You'll build trust, you'll become friends. 

Which you'll think is great, until the end of the game when you find out you have to sacrifice his life to win. This is an hours-long affair during which he will lie bleeding on the floor, screaming "WHY, DAVID? WHY?!?!?" over and over again at the screen. Did I mention that the guy knows your name?